1. think
Sequential thinking tool for breaking down complex biomedical problems systematically. MUST be used first for any biomedical research task.
2. search
Unified search tool supporting both natural language queries and structured field syntax for cross-domain biomedical searches across articles, trials, and variants.
3. fetch
Retrieve full details for a single article, trial, or variant using their respective IDs (PMID, DOI, NCT number, or variant ID).
4. article_searcher
Search PubMed/PubTator3 and preprint servers for biomedical literature with entity annotations.
5. article_getter
Fetch detailed article information using PMID or DOI, with optional full-text retrieval.
6. trial_searcher
Search clinical trials from ClinicalTrials.gov or NCI Clinical Trials Search API with advanced filtering options.
7. trial_getter
Fetch comprehensive trial details from either ClinicalTrials.gov or NCI database.
8. trial_protocol_getter
Retrieve protocol information specifically from ClinicalTrials.gov trials.
9. trial_references_getter
Fetch trial-related publications and references from ClinicalTrials.gov.
10. trial_outcomes_getter
Retrieve outcome measures and results data from ClinicalTrials.gov trials.
11. trial_locations_getter
Fetch site locations and contact information for ClinicalTrials.gov trials.
12. variant_searcher
Search MyVariant.info database for genetic variant information with significance filtering.
13. variant_getter
Fetch comprehensive variant details including TCGA, 1000 Genomes, and cBioPortal annotations.
14. nci_organization_searcher
Search NCI's organization database for cancer research institutions and centers.
15. nci_organization_getter
Retrieve detailed organization information by NCI organization ID.
16. nci_intervention_searcher
Search NCI's intervention database for drugs, devices, and medical procedures used in cancer trials.
17. nci_intervention_getter
Fetch detailed intervention information by NCI intervention ID.
18. nci_biomarker_searcher
Search biomarkers used in clinical trial eligibility criteria through NCI database.
19. nci_disease_searcher
Search NCI's controlled vocabulary of cancer conditions and disease terms.
20. gene_getter
Retrieve real-time gene information from MyGene.info including official names, summaries, and database links.
21. disease_getter
Get disease definitions and synonyms from MyDisease.info for condition expansion in searches.
22. drug_getter
Fetch drug and chemical compound information from MyChem.info including properties and annotations.
23. fda_adverse_events_searcher
Search FDA Adverse Event Reporting System (FAERS) for post-market drug safety reports.
24. fda_drug_labels_searcher
Search FDA drug labels (SPL) for official prescribing information and regulatory data.
